Empowered Perimenopause With Francesca Liparoti

Episode 55: Autoimmunity, Perimenopause & Your Immune System: What Every Woman Needs to Know

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Welcome back to the Empowered Perimenopause podcast with me your host, Francesca Liparoti, Nutritional Therapist and women’s health guide.

This week we’re tackling a topic that so many women in midlife struggle with but rarely get answers about: autoimmunity.

If you’ve ever been told you have thyroid problems, unexplained joint pain, or strange symptoms that flare and fade without reason, this episode is for you.

In this episode, you’ll learn:

• What autoimmunity is and why your immune system can sometimes turn on your own body.
• The link between perimenopause and autoimmune flares, and why hormonal changes, especially in oestrogen, play such a big role.
• Dr Alessio Fasano’s “autoimmune triad”: the three factors needed for autoimmunity to take hold.
• Why gut health and leaky gut are central to immune balance.
• The most common triggers that spark autoimmunity in women, including stress, infections, toxins, and hormonal shifts.
• A closer look at Hashimoto’s thyroiditis, one of the most common autoimmune conditions for women in perimenopause.
• Five practical steps you can start taking today to calm your immune system and support your health.

Key takeaways:

• Autoimmunity doesn’t strike randomly, it develops from a mix of genetics, gut health, and triggers.
• Perimenopause is a window of vulnerability because of hormonal shifts, but it’s also an opportunity to strengthen your foundations.
• With the right support for your gut, nervous system, and environment, you can calm immune overdrive and protect your long-term health.
• Your body isn’t broken, it’s communicating with you.

Listen to episode 55 now, which will leave you feeling empowered with knowledge, clarity, and hope.

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Get in touch! If you have any questions from this episode that you’d like me to address on a future episode or if you have suggestions for topics and or guests you’d like me to cover and chat with on the show, let me know! You can email me on francesca@francescaliparoti.com or drop me a DM on Instagram.