
In this episode, I answer a brilliant listener question from “Laura,” a 46-year-old woman navigating perimenopause with a long-standing history of chronic cholecystitis — inflammation of the gallbladder without gallstones. We explore how gallbladder health ties into oestrogen detoxification, what this means for perimenopause symptoms, and whether being on oestrogen hormone therapy (HRT) can increase the risk of gallstones.
Tune in to learn:
- The crucial role of bile and how the liver and gallbladder work together
- How sluggish bile flow can contribute to oestrogen dominance
- The connection between gallbladder dysfunction and perimenopausal symptoms like breast pain, worsened PMS, and heavy periods
- Whether oestrogen therapy can raise your risk of gallstones — and which forms are shown to be safer
- Practical, natural ways to support your liver, bile production, and gallbladder health
Whether you’ve had gallbladder issues or are just keen to support hormone balance through perimenopause, this episode is packed with empowering insights and takeaways.
Dive in and listen to episode 39 on your favourite podcast platform. Enjoy!
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If you have any questions from this episode that you’d like me to address on a future episode or if you have suggestions for topics and or guests you’d like me to cover and chat with on the show, let me know! You can email me on francesca@francescaliparoti.com or drop me a DM on Instagram.


