Empowered Perimenopause With Francesca Liparoti

Episode 35: Autoimmunity & Perimenopause: Triggers, Gut Health, and What You Can Do

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In this episode, I’m building on last week’s discussion about how hormonal shifts during perimenopause impact all 12 body systems—and how they can play a role in triggering or worsening autoimmune conditions.

I discuss:

• Why autoimmunity often first appears or flares during perimenopause
• The role of gut permeability (aka “leaky gut”) in immune dysregulation
• Common autoimmune triggers (including stress, infections, and toxins)
• How oestrogen influences immune function
• The 5R Healthy Gut Reset framework for supporting gut health
• Practical food and lifestyle tips to reduce inflammation and support your immune system

If you’ve been dealing with fatigue, brain fog, joint pain, or flare-ups of existing autoimmune symptoms, this episode will help you understand the “why” behind what you’re feeling—and what you can start doing today to support your body.

Dive in and listen to episode 35 on your favourite podcast platform. Enjoy!

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Get in touch!

If you have any questions from this episode that you’d like me to address on a future episode or if you have suggestions for topics and or guests you’d like me to cover and chat with on the show, let me know! You can email me on francesca@francescaliparoti.com or drop me a DM on Instagram.